ITOSIN INJECTION
Composition
Each ml contains:
Tylosin Tartrate 200mg Description:
Description
Tylosin is a macrolide antibiotic with a bacteriostatic action against mainly Gram-positive bacteria like Campylobacter, Mycoplasma, Pasteurella, Staphylococcus, Streptococcus and Treponema spp.
Indications
Gastrointestinal and respiratory infections caused by tylosin sensitive micro-organisms, like Campylobacter, Mycoplasma, Pasteurella, Staphylococcus, Streptococcus and Treponema spp., in calves, cattle, goats, sheep and swine.
Contra-indications
Hypersensitivity to Tylosin.
Concurrent administration with penicillines, cephalosporines, quinolones and cycloserine. Side effects:
After intramuscular administration local reactions can occur, which disappear in a few days. Diarrhoea, epigastric pain and skin sensitization can occur.
Dosage & Administration
For intramuscular administration:
General: 1 ml. per 10 – 20 kg. Body weight for 3 – 5 days.
Withdrawal Times
– For meat : 10 days.
– For milk : 3 days.
Warning
Keep out of reach of children.
Available Packing
10ml, 20ml, 50ml, 100ml and 500ml.
TRIPOXD INJECTION
Composition
Each 100 ml solution contains
Oxytetracycline as HCl 15.0gm
Tripelennamine HCl 1.00gm
Dexamethasone sodium phosphate 0.05gm
Indications
TRIPOXD is active against oxytetracycline sensitive micro-organisms, including Rickettsiae, Brucella, Haemolytic Streptococci and some large viruses.
Species: Cattle and Sheep.
Dosage & Administration
For deep intramuscular use or very slow intravenous use. The recommended dosage is as follows:
Species Dose ml / kg
Cattle 1 – 2 ml / 50 kg
Cow 4 – 8 ml / 200 kg
Sheep 0.5 – 1 ml / 10 kg
Contra-indications & Warnings
This product should not be used in pregnant animals. Occasional allergies do occur but these are rare.
TRIPOXD should not be diluted with solutions of calcium salts. This product should not be used in uncomplicated viral infections.
This product should not be used in calves with severe respiratory distress.
Withdrawal Period
Milk must not be used for human consumption during treatment or for 72 hours thereafter.
Animals should not be slaughtered for human consumption during treatment or for 28 days thereafter.
Precautions
Keep out of reach of children. Store in a cool place, below 25 ºC and protect from light. Avoid contamination during use. Once the vial is broached use contents within 4 weeks.
Wash hands after use. This product contains dimethylacetamide (DMAC) and care should be taken to prevent absorption through the skin.
Available Packing
10ml, 25ml, 50ml and 100ml.
TYLOSULPHT INJECTION
Sulphamethoxypyridazine 15gm
Trimethoprim 3.0gm
Tylosin tartarate 5.0gm
Indications
For use in horses, cattle, pigs, sheep, goats, dogs and cats for the treatment of diseases of the: Respiratory tract; pneumonia, bronchitis, Digestive tract; gastritis, enteritis, gastroenteritis, traumatic reticulitis, Urogenital tract; pyometra, metritis, vaginitis, nephritis, Local and generalized infections; mastitis, foot infections, wound infections, septicaemias.
Up to 80% of Staphylococcus intermedius isolates have been shown to be susceptible to sulphadimethyl pyrimidine/ trimethoprim/tylosin. High percentages of sensitivity are also found in infections with Proteus mirabilis, Bacillus anthracis, Hemophilus influenza, Pasteurella spp, Salmonella spp., Escherichia coli., Staphylococcus spp. & Streptococcus spp.
Leptospira, Pseudomonas, Erysipelothrix and M. tuberculosis organisms are NOT sensitive to sulpha-trimethoprim. Amphoprim offers a cost-effective option for those conditions where susceptible infection is present.
Mode of Action
The Sulphadimethyl pyrimidine – trimethoprim – tylosin combination acts synergistically to inhibit bacterial cell metabolism by blocking two sequential steps of the enzymatic pathway leading to the synthesis of bacterial folic acid. The effect is bactericidal in susceptible organisms, including Gram-positive and Gram- negative bacteria.
There are advantages having a water based injectable: ease of injection, less risk of intravascular heamolysis or extra vascular necrosis, neutral pH and faster bioavailability.
Contra-indications
Do not administer to animals with known sulphonamide sensitivity.
Dosage & Administration
1 mL/15 kg bodyweight daily by subcutaneous, intramuscular or intravenous injection for 3 – 5 days. For i.m or s.c injections over 5 mL administer in 2 or more sites.
Note
the recommended dose should not be exceeded in the horse. Give in the anterior half of the neck in food producing animals.
Storage
Store below 40 °C (104 °F), preferably between 15 and 30 °C (59 and 86°F). Protect from light. Protect from freezing.
Withdrawal Period
Milk: 48 hours Meat: 5 days Horses: 63 days
GENTYLO INJECTION
Composition
Each 100ml contain:
Tylosin tartrate 10 g Gentamycin (as Sulphate) 5 g
Description
Gentamycin belongs to the group of aminoglycosides and acts bactericidal against mainly Gram-negative bacteria like E. coli, Klebsiella, Pasteurella and Salmonella spp. The bactericidal action is based on inhibition of bacterial protein synthesis. Tylosin is a macrolide antibiotic with bacteriostatic action against mainly Gram-positive bacteria like Campylobacter, Mycoplasma, Pasteurella, Staphylococcus, Streptococcus and Treponema spp.
Indications
Gastrointestinal and respiratory infections caused by tylosin and gentamycin sensitive micro-organisms like Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus, Streptococcus and Treponema spp. in calves, goats, poultry, sheep and swine.
Dosage & Administration
Cattle, buffalo (I.M.): 1.5 ml/10 kg – Calves, pigs: 2 ml/10kg
Poultry (S.C.): 0.3-0.5 ml/kg
Contra-indications
Hypersensitivity to gentamycin and/or tylosin.
Administration to animals with a seriously impaired hepatic function. Concurrent administration of penicillines, cephalosporines, quinolones and cycloserine. Administration to animals with an active microbial digestion.
Side Effects
Discoloration of teeth in young animals. Hypersensitivity reactions.
Diarrhea can occur.
Available Packing
10ml, 20ml, 50ml and 100ml